Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Ranitidine. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Ranitidine is a histamine-2 (H2) receptor antagonist commonly used to reduce stomach acid production. Structurally, ranitidine features a substituted furan ring. It works by selectively blocking H2 receptors in the stomach lining, inhibiting the action of histamine, a chemical that stimulates acid secretion. By reducing gastric acid production, ranitidine is effective in treating conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. It is available in various formulations, including oral tablets and injectable solutions. Ranitidine provides relief from acid-related symptoms and promotes the healing of ulcers. While it was widely used for decades, concerns about the presence of low levels of a potential carcinogen led to the withdrawal of many ranitidine products from the market in several countries. Individuals should consult with healthcare professionals for alternative treatment options and the latest safety information.
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