1,4-Dinitrosopiperazine (CAT. No. CP-NIT003, CAS No. 140-79-4) is a nitrosamine-class piperazine derivative supplied by Chemicea, with molecular formula C4H8N4O2 and molecular weight 144.13 g/mol. Also referenced as N,N'-Dinitrosopiperazine (DNP) or Piperazine Impurity 4, this compound is manufactured to controlled specifications for use as a genotoxic/nitrosamine impurity reference standard in pharmaceutical quality-control and regulatory testing, particularly for Buspirone and other piperazine-containing APIs undergoing nitrosamine risk assessment per ICH M7 guidelines. Each lot is characterized by GC and NMR and issued with a full Certificate of Analysis (COA) for identity confirmation and traceability. As a documented nasopharyngeal carcinogen in experimental models, it is intended strictly for regulated laboratory and analytical use, with appropriate handling protocols. Chemicea supplies this reference standard in research-scale pack sizes with global cold-chain shipping.
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