4-Chloro-N-methylpyridine-2-carboxamide with CAS No:882167-77-3 is an impurity standard of Sorafenib.
Sorafenib is a medication used in the treatment of advanced renal cell carcinoma (kidney cancer), hepatocellular carcinoma (liver cancer), and radioactive iodine-resistant thyroid cancer. Chemically, it is a kinase inhibitor that targets multiple signaling pathways involved in tumor growth and angiogenesis. Sorafenib inhibits the activity of kinases such as Raf, VEGFR (vascular endothelial growth factor receptor), and PDGFR (platelet-derived growth factor receptor). By disrupting these pathways, sorafenib helps slow down cancer cell proliferation and reduce the growth of blood vessels that supply tumors. It is typically administered orally in tablet form and is considered an important therapeutic option in the management of certain advanced cancers.
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