Acebrophylline is a bronchodilator and mucoregulatory agent used in the management of respiratory disorders such as asthma and chronic obstructive pulmonary disease (COPD). Structurally, it is a combination of ambroxol, a mucolytic agent, and theophylline, a bronchodilator. Chemically, acebrophylline is a derivative of xanthine, with a theophylline molecule linked to an ambroxol molecule.Acebrophylline works through multiple mechanisms to improve respiratory function. The theophylline component acts as a bronchodilator by relaxing the smooth muscles of the airways, leading to bronchodilation and improved airflow. Additionally, the ambroxol component acts as a mucolytic agent by thinning and loosening mucus secretions in the airways, making it easier to clear them through coughing. This helps to reduce airway obstruction and improve expectoration of mucus, further enhancing respiratory function.
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