Acenocoumarol is an anticoagulant medication belonging to the class of vitamin K antagonists (VKAs). Chemically, it is a derivative of coumarin. Acenocoumarol functions by inhibiting the synthesis of vitamin K-dependent clotting factors, primarily factors II, VII, IX, and X, in the liver. This action leads to the prevention of blood clot formation and is utilized therapeutically to treat and prevent thromboembolic disorders such as deep vein thrombosis (DVT), pulmonary embolism (PE), and atrial fibrillation (AF). Acenocoumarol requires careful monitoring of its anticoagulant effect through regular blood tests, as its dosage needs adjustment based on individual patient response to maintain therapeutic efficacy while minimizing the risk of bleeding complications.
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