Ademethionine, also known as S-adenosyl-L-methionine (SAMe), is a naturally occurring compound synthesized from the amino acid methionine and adenosine triphosphate (ATP). It serves as a methyl donor in various biochemical reactions, including methylation of DNA, proteins, and neurotransmitters. Ademethionine plays essential roles in numerous physiological processes, including neurotransmitter synthesis, detoxification, and regulation of gene expression. It is available as a dietary supplement and has been investigated for its potential therapeutic benefits in treating various conditions, including depression, osteoarthritis, liver disease, and fibromyalgia. Ademethionine supplementation has shown promising results in some studies, although further research is needed to fully understand its mechanisms of action and therapeutic potential.
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