Alosetron is a medication classified as a selective serotonin 5-HT3 receptor antagonist, primarily used in the management of irritable bowel syndrome with diarrhea (IBS-D). Chemically, it is a serotonin receptor antagonist. Alosetron works by blocking the action of serotonin on 5-HT3 receptors in the gut, leading to decreased gastrointestinal motility and secretion. This results in relief from symptoms such as diarrhea, abdominal pain, and urgency associated with IBS-D. Alosetron is typically prescribed for women with severe symptoms of IBS-D who have not responded to other treatments.
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