Amfenac is a nonsteroidal anti-inflammatory drug (NSAID) used primarily in ophthalmology as an eye drop formulation for the treatment of postoperative inflammation and pain following cataract surgery. Chemically, it is a derivative of fenamate. Amfenac works by inhibiting the enzyme cyclooxygenase (COX), thereby reducing the production of prostaglandins, which are mediators of inflammation and pain. By suppressing inflammation and pain in the eye, amfenac helps to improve patient comfort and promote healing after cataract surgery. It is typically administered as a topical ophthalmic solution several times daily for a short duration following surgery.
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