Amikacin is a broad-spectrum aminoglycoside antibiotic used to treat various bacterial infections, particularly those caused by aerobic gram-negative bacteria and some gram-positive bacteria. Chemically, it is a semisynthetic derivative of kanamycin.Amikacin is commonly used to treat severe infections such as nosocomial pneumonia, septicemia, urinary tract infections, and certain types of tuberculosis. It is usually administered intravenously or intramuscularly due to its poor oral absorption. Despite its efficacy, amikacin carries a risk of serious adverse effects, including nephrotoxicity, ototoxicity, and neuromuscular blockade, particularly with prolonged or high-dose therapy.
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