Amprolium is a synthetic antiprotozoal agent primarily used in veterinary medicine to prevent and treat coccidiosis, a common intestinal disease caused by protozoan parasites belonging to the genus Eimeria. Chemically, amprolium is a thiamine analog, structurally similar to vitamin B1, and acts by competitively inhibiting thiamine uptake in the coccidia, disrupting their metabolism and preventing their multiplication. It is particularly effective against the Eimeria species responsible for coccidiosis in poultry, cattle, sheep, and other livestock. Amprolium is available in various formulations, including oral solutions and feed additives, and is typically administered prophylactically in feed or water to prevent outbreaks of coccidiosis in poultry and other livestock raised in intensive farming systems.
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