Anhydrotetracycline is a derivative of tetracycline, an antibiotic produced by certain species of Streptomyces bacteria. Chemically, it is closely related to tetracycline, featuring a tetracyclic naphthacene ring structure. Anhydrotetracycline is formed when tetracycline loses a water molecule from its molecular structure, typically through exposure to heat or acidic conditions. Although anhydrotetracycline itself does not possess antibiotic activity, it serves as a precursor for the synthesis of modified tetracycline derivatives with enhanced pharmacological properties. These derivatives can exhibit improved antibiotic efficacy, reduced resistance development, and altered pharmacokinetic profiles compared to the parent compound.
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