Arteether is a derivative of artemisinin, a naturally occurring compound extracted from the sweet wormwood plant (Artemisia annua). Structurally, it is a sesquiterpene lactone peroxide. Chemically, arteether is a semi-synthetic derivative of artemisinin, with an ether linkage at the C-10 position. This modification enhances its solubility and pharmacokinetic properties, improving its efficacy as an antimalarial agent.Arteether is an antimalarial medication used in the treatment of uncomplicated Plasmodium falciparum malaria. It belongs to the artemisinin-based combination therapy (ACT) class of antimalarial drugs, which are recommended by the World Health Organization (WHO) as first-line treatment for uncomplicated falciparum malaria in regions where the parasite has developed resistance to other antimalarial drugs.
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