Artemisinin is a natural compound derived from the sweet wormwood plant, Artemisia annua. It is a sesquiterpene lactone with a unique peroxide bridge structure. Artemisinin and its derivatives, such as artesunate and artemether, are widely used as first-line treatments for malaria, particularly for cases caused by Plasmodium falciparum, the most deadly malaria parasite species. Artemisinin-based combination therapies (ACTs) are recommended by the World Health Organization (WHO) as the most effective treatment for uncomplicated malaria.Its rapid onset of action and ability to kill parasites at all stages of development make it highly effective in treating malaria. Additionally, artemisinin and its derivatives have been studied for their potential anticancer properties and other therapeutic applications, though further research is needed to explore their full potential in these areas.
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