Arterolane is a synthetic antimalarial drug belonging to the trioxolane class of compounds. It is used in combination with piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria, particularly in regions where resistance to other antimalarial drugs such as chloroquine and sulfadoxine-pyrimethamine is prevalent.When combined with piperaquine, arterolane-piperaquine acts synergistically to provide rapid and effective clearance of malaria parasites from the bloodstream. This combination therapy has demonstrated high efficacy, rapid parasite clearance, and a low risk of recurrence, making it a valuable tool in the fight against malaria.
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