Avilamycin is a cyclic polypeptide antibiotic belonging to the class of orthosomycins. Structurally, it consists of a macrocyclic core with several amino acid residues. Chemically, avilamycin is composed of a cyclic core containing 10 amino acids, including non-proteinogenic amino acids such as 4-epi-valine and 3-hydroxy-4-methylproline. This complex structure is responsible for its antibiotic activity against susceptible bacteria.Avilamycin is primarily used in veterinary medicine as a feed additive for the prevention and treatment of certain bacterial infections in livestock, particularly poultry and swine. Avilamycin works by inhibiting bacterial protein synthesis, specifically targeting the 50S ribosomal subunit. This mechanism of action prevents the growth and replication of susceptible bacteria, thereby controlling infections and promoting animal health.
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