Calcitriol EP Impurity B with CAS No: 66791-71-7 is an impurity standard of Calcitriol.
Calcitriol is the active form of vitamin D3 in the body and plays a crucial role in calcium and phosphorus homeostasis. It is a steroid hormone that regulates the absorption of calcium and phosphate in the small intestine, promotes bone mineralization, and modulates parathyroid hormone (PTH) secretion. Calcitriol is synthesized in the kidneys from its precursor, vitamin D3 (cholecalciferol), through a series of enzymatic conversions. It acts by binding to vitamin D receptors in the intestines, bones, and parathyroid glands, influencing the expression of various genes involved in calcium metabolism. Clinically, calcitriol is used to treat conditions associated with disrupted calcium and phosphate balance, such as hypocalcemia in chronic kidney disease, hypoparathyroidism, and certain bone disorders. Additionally, it is used in the management of osteoporosis to support bone health.
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