Cefuroxime Axetil EP Impurity A with CAS No: 123458-61-7 is an impurity standard of Cefuroxime Axetil.
Cefuroxime axetil is a cephalosporin antibiotic characterized by its beta-lactam ring structure. As an acetoxyethyl ester prodrug, it undergoes enzymatic hydrolysis to yield the active form, cefuroxime, upon oral administration. The beta-lactam ring is central to its mechanism of action, as cefuroxime inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to bacterial cell lysis. This antibiotic is effective against a range of Gram-positive and Gram-negative bacteria, making it suitable for treating respiratory tract, skin, and urinary tract infections. The esterification at the 1-position enhances its oral bioavailability, facilitating convenient outpatient treatment. The use of cefuroxime axetil is guided by healthcare professionals to ensure proper dosing, completion of the prescribed course, and effective management of specific bacterial infections.
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