Erythromycin Ethyl Succinate, chemically identified as the 2'-O-(ethyl succinate) ester of Erythromycin A, is a macrolide antibiotic ester prodrug with molecular formula C₄₃H₇₅NO₁₆ and molecular weight 862.06 g/mol, derived from Erythromycin, which is produced by fermentation of Saccharopolyspora erythraea. Esterification at the 2'-hydroxyl group of the desosamine sugar masks the bitter taste and improves acid stability relative to Erythromycin base, making it well suited to oral suspensions and tablets; after absorption, the ester is hydrolysed to active Erythromycin, which exerts bacteriostatic activity by binding the 23S rRNA of the bacterial 50S ribosomal subunit and inhibiting protein synthesis. Supplied by Chemicea as a well-characterized, high-purity reference standard, it supports analytical method development, assay and related-substance testing, dissolution and stability studies, and quality-control testing throughout Erythromycin Ethyl Succinate drug substance and oral suspension/tablet formulation development, in accordance with USP, EP, and BP monograph requirements. Each batch is supplied with a comprehensive Certificate of Analysis supported by HPLC, ¹H-NMR, and Mass Spectrometry characterization data, ensuring dependable analytical traceability for regulatory and pharmaceutical R&D applications. CAS No. 1264-62-6 | Explore complete technical documentation, Safety Data Sheet (SDS), and pricing.
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