Fluticasone Furoate, chemically defined as S-(Fluoromethyl) 6α,9-difluoro-17α-[(furan-2-carbonyl)oxy]-11β-hydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17β-carbothioate, is a trifluorinated androstane-based synthetic corticosteroid with molecular formula C₂₇H₂₉F₃O₆S and molecular weight 538.58 g/mol. Structurally, it is distinguished by a 17α-furoate ester, which contributes to its very high glucocorticoid receptor binding affinity and prolonged retention in respiratory tissue, supporting once-daily dosing. It is used intranasally for allergic rhinitis and by oral inhalation, alone or in combination with long-acting bronchodilators, for asthma and chronic obstructive pulmonary disease (COPD). Supplied by Chemicea as a well-characterized, high-purity reference standard, it is intended for analytical method development, assay and related-substance testing, dissolution, delivered-dose and stability studies, and quality-control testing throughout Fluticasone Furoate drug substance, nasal-spray, and inhalation-powder formulation development. Each batch is supplied with a comprehensive Certificate of Analysis supported by HPLC, ¹H-NMR, and Mass Spectrometry characterization data, ensuring dependable analytical traceability for regulatory and R&D applications. CAS No. 397864-44-7 | Explore complete technical documentation, Safety Data Sheet (SDS), and pricing.