Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Lenalidomide. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds.
Lenalidomide is a pharmaceutical agent with diverse applications, prominently utilized in the treatment of multiple myeloma, myelodysplastic syndromes, and certain types of lymphomas. It belongs to the class of immunomodulatory drugs and exerts its therapeutic effects through various mechanisms. Lenalidomide has immunomodulatory, anti-angiogenic, and direct antitumor properties. It enhances the immune systems response against cancer cells, inhibits the growth of new blood vessels that support tumor growth, and induces apoptosis in certain cancer cells. Additionally, lenalidomide has shown efficacy in treating anemia associated with myelodysplastic syndromes.
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