Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Amodiaquine. Nitrosamines are part of a broader class of compound
Amodiaquine is an antimalarial medication used to treat and prevent malaria caused by Plasmodium falciparum. Chemically, it is a 4-aminoquinoline derivative related to chloroquine. Amodiaquine is effective against chloroquine-resistant strains of the malaria parasite. Its mechanism of action involves interfering with the parasites ability to break down hemoglobin, essential for its survival. Amodiaquine is often used in combination with other antimalarial drugs for increased efficacy and to reduce the risk of drug resistance.
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