Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Articaine. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Articaine is a local anesthetic commonly used in dentistry for dental procedures. It belongs to the amide group of local anesthetics and is known for its quick onset and effective pain relief. Articaine is often used for procedures such as tooth extractions, fillings, and other dental work. One notable feature of articaine is its ability to penetrate both hard and soft tissues effectively, making it suitable for various dental applications. It typically comes with a vasoconstrictor, such as epinephrine, which helps to prolong the anesthetic effect and reduce bleeding at the site. As with any medication, it is important for dental professionals to consider individual patient factors and follow appropriate guidelines for administration to ensure the safe and effective use of articaine during dental procedures.
Buy high quality N-Nitroso Articaine from Chemicea Pharmaceuticals. Chemicea Pharmaceuticals is one of the leading manufacturer and exporter of N-Nitroso Articaine.

N-Nitroso Articaine

CAT. No. CP-A83011
CAS. No. NA
Mol. F. C13H19N3O4S
Mol. Wt. 313.37
Stock Status In Stock
Sample PDF VIEW COA Sample PDF VIEW MSDS
  • Category: Impurity Standards
  • Synonyms: NA
  • Chemical Name: methyl 4-methyl-3-(2-(nitroso(propyl)amino)propanamido)thiophene-2-carboxylate

FAQ

It is a nitrosamine impurity that can form during the synthesis, storage, or handling of Articaine, commonly used in pharmaceuticals.

It is subject to strict guidelines from regulatory bodies like the FDA and EMA to ensure safe levels in medications.

It forms when Articaine interacts with nitrosating agents, especially under conditions involving heat, moisture, or acidity.

Through the use of appropriate materials, optimized storage conditions, pH control, and routine testing.

Techniques like GC-MS (high sensitivity), LC-MS (accurate measurement), and HPLC-MS (flexible analysis) are employed.

Chemicea provides COA, H-NMR, MASS, HPLC, and TGA reports as standard, with additional reports like CNMR, IR, UV, DEPT, Water content, and CHNS available upon request.

Yes, they meet the standards of USFDA, EMA, ANVISA, TGA, PMDA, and other global health agencies.

N-Nitroso Articaine is stable for shipping at room temperature, with specific storage requirements detailed in the COA.

Yes, both standard and customized pack sizes are available to meet specific client needs.

Chemicea provides N-Nitroso Articaine as a reference standard, aiding in method validation, impurity analysis, and regulatory compliance for quality control.

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