Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Candesartan. Nitrosamines are part of a broader class of compound
Candesartan is an angiotensin II receptor blocker (ARB) used in the treatment of hypertension and heart failure. Chemically, it is a prodrug that, after oral administration, is converted to its active form, candesartan. Candesartan works by blocking the action of angiotensin II, a hormone that constricts blood vessels, leading to reduced blood pressure and improved cardiac function. It is administered orally and may be prescribed alone or in combination with other antihypertensive medications. Candesartan cilexetils chemistry involves its conversion to candesartan in the body, optimizing its therapeutic effects.
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