Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Celiprolol. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Celiprolol is a cardioselective beta-1 adrenergic receptor antagonist with vasodilatory properties, making it a beta-blocker with additional beta-2 agonist activity. Structurally, it belongs to the aryloxypropanolamine class. Celiprolol is used in the treatment of hypertension and certain cardiovascular conditions. By blocking beta-1 receptors, it reduces heart rate and blood pressure, while its beta-2 agonist activity leads to vasodilation. Administered orally, celiprolol is valued for its dual mechanism, providing antihypertensive effects with a reduced impact on parameters like heart rate.
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