Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Colistin. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Colistin, a polymyxin antibiotic, is used to treat severe bacterial infections, particularly those caused by multidrug-resistant Gram-negative bacteria. Structurally, it is a polypeptide antibiotic. Colistin disrupts bacterial cell membranes by binding to lipopolysaccharides, resulting in increased permeability and eventual cell death. Administered intravenously or through inhalation, colistin is often considered a last-resort treatment due to its potential for nephrotoxicity and neurotoxicity. Its role has become more critical in the face of antibiotic-resistant strains, where colistin remains effective against certain bacteria that are resistant to other antibiotics. Buy high quality N-Nitroso colistin b Hydrogen methanesulfonate 2 from Chemicea Pharmaceuticals. Chemicea Pharmaceuticals is one of the leading manufacturer and exporter of N-Nitroso colistin b Hydrogen methanesulfonate 2.
Chemical Name:((((3R,6S,9S,12S,15R,18S,21S)-3-((R)-1-hydroxyethyl)-21-((S)-2-((2S,5S)-2-((R)-1-hydroxyethyl)-5-(6-methylheptanamido)-4-oxo-7-((sulfomethyl)amino)heptanamido)-4-((sulfomethyl)amino)butanamido)-12,15-diisobutyl-18-(2-(nitroso(sulfomethyl)amino)ethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosane-6,9-diyl)bis(ethane-2,1-diyl))bis(azanediyl))dimethanesulfonic acid
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