Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Crizotinib. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Crizotinib, a tyrosine kinase inhibitor, is integral in treating non-small cell lung cancer (NSCLC) with specific genetic alterations. Structurally, it inhibits ALK, ROS1, and MET receptor tyrosine kinases, impeding aberrant signaling pathways in cancer cells. Administered orally, crizotinib stands at the forefront of precision medicine, demonstrating efficacy against advanced or metastatic cancers characterized by ALK or ROS1 gene rearrangements. This targeted approach exemplifies the evolving landscape of cancer therapy, where molecularly tailored treatments like crizotinib play a pivotal role in improving patient outcomes.
Buy high quality N-Nitroso Crizotinib from Chemicea Pharmaceuticals. Chemicea Pharmaceuticals is one of the leading manufacturer and exporter of N-Nitroso Crizotinib.