Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Eravacycline. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Eravacycline is a novel tetracycline antibiotic designed to address multidrug-resistant bacterial infections. It belongs to the class of fluorocyclines and demonstrates broad-spectrum activity against Gram-positive and Gram-negative bacteria, including strains resistant to other tetracycline antibiotics. Eravacycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, disrupting the growth and reproduction of bacteria. It is used to treat complicated intra-abdominal infections and complicated urinary tract infections. This antibiotic is administered intravenously and is valued for its efficacy against challenging bacterial strains. As with any antibiotic, appropriate use and adherence to healthcare professional recommendations are crucial to optimize therapeutic outcomes and minimize the risk of antibiotic resistance.
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