Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Esmolol. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Esmolol is a short-acting, cardioselective beta-1 adrenergic receptor antagonist, commonly referred to as a beta-blocker. Structurally, it is an ester derivative of propranolol. Esmolol is used in the treatment of acute cardiac conditions, such as supraventricular tachycardia and atrial fibrillation, where rapid heart rate control is necessary. Administered intravenously, esmolol quickly crosses the blood-brain barrier, exerting its effects on the heart by blocking beta-1 receptors. Its short duration of action allows for precise control over heart rate and makes it suitable for situations requiring rapid titration and reversibility. Esmolol plays a vital role in managing acute cardiac arrhythmias and hypertensive emergencies.
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