Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Fenfluramine. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Fenfluramine is a medication that was historically used as an appetite suppressant to aid in weight loss. It works by increasing the levels of serotonin in the brain, which leads to a reduction in appetite.The drugs use was particularly linked to an increased risk of pulmonary hypertension and heart valve disorders. While it once played a role in weight management, its withdrawal underscores the importance of prioritizing patient safety and monitoring potential long-term effects of medications.
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