Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Imatinib. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds.
Imatinib is marketed under the brand name Gleevec (or Glivec) and targeted cancer therapy medication used to treat certain types of cancer. Imatinib is belongs to a class of drugs known as tyrosine kinase inhibitors (TKIs), which work by inhibiting specific enzymes called tyrosine kinases that are involved in the growth and spread of cancer cells. Imatinib has revolutionized the treatment of certain cancers and has shown remarkable effectiveness in improving outcomes for patients with these conditions.
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