Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Imidapril. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Imidapril is an angiotensin-converting enzyme (ACE) inhibitor used in the treatment of hypertension and congestive heart failure. Its chemical structure includes a dicarboxylate moiety, making it distinct within the ACE inhibitor class. Imidapril works by inhibiting the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor, thereby promoting vasodilation and reducing blood pressure. This medication is known for its high lipophilicity, enhancing its tissue penetration and therapeutic efficacy. Imidapril demonstrates a favorable safety profile and is commonly prescribed to patients with cardiovascular conditions to help manage blood pressure and improve cardiac function.
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