Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Isoxsuprine. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Isoxsuprine is a vasodilator belonging to the 1,4-dihydroquinoline class, with a chemical structure comprising a quinoline ring fused to a cyclopentane ring. Known chemically as 1-(4-hydroxyphenyl)-3-(1-methyl-4-isoquinolinyl)-1-propanol, isoxsuprine acts as a β-adrenergic agonist, exerting its therapeutic effects by stimulating β-adrenergic receptors. This stimulation leads to the relaxation of smooth muscle in blood vessels, particularly in the peripheral vasculature, resulting in increased blood flow. Isoxsuprine is used clinically to improve circulation in conditions such as peripheral vascular disease and Raynauds phenomenon.
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