Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Lercanidipine. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds.
Lercanidipine is a dihydropyridine calcium channel blocker used for the treatment of hypertension. Chemically, it is classified as a dihydropyridine derivative. Lercanidipine functions by selectively blocking calcium channels in vascular smooth muscle, leading to vasodilation and a subsequent reduction in blood pressure. Its chemical structure contributes to its calcium channel blocking activity. Lercanidipine is known for its long duration of action, allowing for once-daily dosing. As an antihypertensive medication, it is commonly prescribed to manage high blood pressure, aiding in the relaxation of blood vessels and improving blood flow. Lercanidipine efficacy in hypertension treatment underscores its significance in cardiovascular medicine, providing an option for patients requiring effective and well-tolerated long-term blood pressure control.
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