Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Macitentan. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds.
Macitentan is a medication used in the treatment of pulmonary arterial hypertension (PAH), a rare and serious condition characterized by high blood pressure in the arteries of the lungs. Macitentan is classified as an endothelin receptor antagonist. Macitentan is typically available in oral tablet form
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