Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Metolazone. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Metolazone is a medication classified as a thiazide-like diuretic. Metolazone is primarily used to treat conditions involving excessive fluid retention and edema, often associated with conditions like congestive heart failure, kidney disorders, liver disease and high blood pressure (hypertension).
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