Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Midazolam. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds.
Midazolam is a short-acting benzodiazepine medication commonly used for its sedative, anxiolytic, and hypnotic properties. It is frequently employed in medical settings, such as before surgical or medical procedures, to induce sedation and reduce anxiety. Midazolam enhances the effect of a neurotransmitter called gamma-aminobutyric acid (GABA) in the brain, leading to a calming effect on the central nervous system. This medication is known for its rapid onset of action and relatively short duration, making it well-suited for short-term sedation needs. In addition to its use in procedural sedation, midazolam may be administered in emergency situations or critical care settings.
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N-Nitroso Midazolam EP Impurity E

CAT. No. CP-M85012
CAS. No. NA
Mol. F. C16H14ClFN4O
Mol. Wt. 332.76
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Product Description


  • Category:Impurity Standards
  • Synonyms:N-Nitroso Midazolam Amino Compound
  • Chemical Name:(8-chloro-5-(2-fluorophenyl)-1-nitroso-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methanamine

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