Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Moexipril. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Moexipril is an angiotensin-converting enzyme (ACE) inhibitor used primarily for the treatment of hypertension and congestive heart failure. Its chemical structure includes a dipeptide-like moiety. As an ACE inhibitor, moexipril blocks the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. This action results in vasodilation, reduced aldosterone secretion, and decreased sodium retention, contributing to its antihypertensive effects. Moexipril is typically administered orally, and its long duration of action allows for once-daily dosing. Besides its use in hypertension, it may also be prescribed for heart failure and other cardiovascular conditions. As with other ACE inhibitors, moexipril should be used under the guidance of healthcare professionals.
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