Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Nicardipine. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds.
Nicardipine is a medication classified as a calcium channel blocker (CCB). It is primarily used to treat high blood pressure (hypertension) and certain heart conditions.Nicardipine works by inhibiting the influx of calcium ions into smooth muscle cells of blood vessels and the heart. This leads to relaxation of blood vessels, reduced peripheral vascular resistance and decreased heart workload.Nicardipine is available in various forms, including oral capsules and intravenous (IV) solutions.
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