Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Nefopam. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Nefopam is a non-opioid analgesic used for the management of moderate to severe pain. Its chemical structure is distinct, belonging to the benzoxazocine class. Nefopams exact mechanism of action is not fully understood, but it is believed to involve multiple pathways, including inhibition of the reuptake of serotonin, norepinephrine, and dopamine. Unlike opioids, nefopam does not bind to opioid receptors, making it a non-narcotic option for pain relief. It is particularly useful in postoperative pain, musculoskeletal pain, and chronic pain conditions.
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