Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Nisoldipine. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Nisoldipine is a dihydropyridine calcium channel blocker used to treat hypertension (high blood pressure). Structurally, it is characterized by a dihydropyridine ring and a nitrophenyl substituent. Nisoldipine exerts its antihypertensive effects by inhibiting the influx of calcium ions through voltage-gated calcium channels in vascular smooth muscle cells, resulting in vasodilation and decreased peripheral vascular resistance. This action leads to a reduction in blood pressure and increased blood flow. Nisoldipine is typically administered orally, and its extended-release formulations allow for once-daily dosing, improving patient adherence to treatment.
Buy high quality N-Nitroso Nisoldipine from Chemicea Pharmaceuticals. Chemicea Pharmaceuticals is one of the leading manufacturer and exporter of N-Nitroso Nisoldipine.