Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Nortriptyline. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Nortriptyline is a tricyclic antidepressant (TCA) used in the treatment of major depressive disorder. Structurally related to amitriptyline, it acts by inhibiting the reuptake of neurotransmitters such as serotonin and norepinephrine in the brain. This results in increased levels of these neurotransmitters in the synaptic cleft, which contributes to mood stabilization. Nortriptyline is also prescribed for certain types of chronic pain, such as neuropathic pain and migraine prophylaxis.
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