Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Reboxetine. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Reboxetine is a selective norepinephrine reuptake inhibitor (NRI) used as an antidepressant to treat major depressive disorder. Unlike some other antidepressants that primarily target serotonin, reboxetine specifically inhibits the reuptake of norepinephrine, a neurotransmitter involved in mood regulation. By blocking the reuptake of norepinephrine, reboxetine increases its concentration in the synaptic cleft, enhancing neurotransmission and potentially alleviating symptoms of depression. This unique mechanism distinguishes reboxetine from other classes of antidepressants.
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