Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Relebactam. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Relebactam is a β-lactamase inhibitor used in combination with other antibiotics to enhance their efficacy against multidrug-resistant bacterial infections. Structurally, relebactam is a diazabicyclooctane-derived molecule. It functions as a β-lactamase inhibitor by binding irreversibly to β-lactamase enzymes, which are produced by certain bacteria to confer resistance to β-lactam antibiotics. By inhibiting these enzymes, relebactam restores the activity of co-administered β-lactam antibiotics, such as imipenem. This combination is particularly effective against Gram-negative bacteria, including those producing extended-spectrum β-lactamases (ESBLs) and certain carbapenemases. Relebactam is utilized to treat complicated urinary tract infections, hospital-acquired pneumonia, and other serious bacterial infections when limited treatment options are available. Its application underscores the importance of combination therapies in combating antibiotic resistance and expanding the treatment arsenal for challenging bacterial infections.
Buy high quality N-Nitroso Relebactam from Chemicea Pharmaceuticals. Chemicea Pharmaceuticals is one of the leading manufacturer and exporter of N-Nitroso Relebactam.