Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Telavancin. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Telavancin is a lipoglycopeptide antibiotic designed to combat bacterial infections. Its chemical structure includes a glycopeptide backbone with a lipophilic side chain, enhancing its potency against gram-positive pathogens. Telavancin works by disrupting bacterial cell wall synthesis, leading to increased membrane permeability and eventual cell death. This antibiotic is particularly effective against methicillin-resistant Staphylococcus aureus (MRSA) and other gram-positive bacteria. Due to its broad-spectrum activity and efficacy in treating skin and skin structure infections, telavancin has found applications in challenging cases where other antibiotics might be less effective.
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