Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Tofacitinib. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds.
Tofacitinib is a medication used to treat certain autoimmune diseases, primarily rheumatoid arthritis, psoriatic arthritis and ulcerative colitis. Tofacitinib is classified as a Janus kinase (JAK) inhibitor which means it works by targeting specific enzymes involved in the inflammatory processes associated with these conditions. Tofacitinib is typically taken orally in tablet form.
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