Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Varenicline. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Varenicline is a medication used to aid smoking cessation by helping individuals quit tobacco smoking. It acts as a partial agonist at the α4β2 nicotinic acetylcholine receptors, both stimulating these receptors to a lesser extent than nicotine and blocking nicotine from fully activating them. This dual mechanism reduces the rewarding effects of smoking and alleviates withdrawal symptoms, making it easier for individuals to quit. Varenicline is typically taken orally and is often used as part of a comprehensive smoking cessation program that includes counseling and behavioral support.
Buy high quality N-Nitroso Varenicline from Chemicea Pharmaceuticals. Chemicea Pharmaceuticals is one of the leading manufacturer and exporter of N-Nitroso Varenicline.

N-Nitroso Varenicline

CAT. No. CP-V8028
CAS. No. 2755871-02-2
Mol. F. C13H12N4O
Mol. Wt. 240.27
Stock Status In Stock
Sample PDF VIEW COA Sample PDF VIEW MSDS
  • Category: Impurity Standards
  • Synonyms: NA
  • Chemical Name: 8-Nitroso-7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline

N-Nitroso Varenicline is a structurally characterized nitrosamine impurity of Varenicline, chemically identified as 8-Nitroso-7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline. Chemicea supplies this impurity reference standard with comprehensive analytical characterization data to support pharmaceutical quality, regulatory, and research requirements.

FAQ

N-Nitroso Varenicline is a known related compound associated with the synthesis, degradation, or manufacturing process of Varenicline. It is commonly used as a reference standard for impurity profiling and analytical studies.

N-Nitroso Varenicline helps pharmaceutical companies identify, quantify, and monitor impurities, ensuring product quality and regulatory compliance.

N-Nitroso Varenicline can be analyzed using HPLC, UPLC, LC-MS, GC-MS (where applicable), and other advanced chromatographic and spectroscopic techniques.

Yes, N-Nitroso Varenicline is widely used as a reference standard for qualitative and quantitative analysis of impurities in pharmaceutical products.

It assists in establishing specificity, accuracy, precision, linearity, detection limits, and quantification limits during analytical method validation studies.

N-Nitroso Varenicline can be sourced from Chemicea, a trusted supplier of pharmaceutical impurities, reference standards, metabolites, and analytical research materials for the pharmaceutical industry.

N-Nitroso Varenicline may form during the synthesis, purification, storage, or degradation of the parent drug substance under specific process or environmental conditions.

Chemicea provides COA, H-NMR, MASS, HPLC, and TGA reports as standard with N-Nitroso Varenicline. Additional reports such as CNMR, IR, UV, DEPT, Water Content, and CHNS can be provided upon request, subject to availability.

The CAS number for N-Nitroso Varenicline is 2755871-02-2.

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