Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Venetoclax. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds.
Venetoclax is a BCL-2 inhibitor prescribed for the treatment of certain blood cancers, notably chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML). Operating by inhibiting the B-cell lymphoma-2 (BCL-2) protein, Venetoclax disrupts the survival mechanisms of cancer cells, triggering programmed cell death. It is often utilized in combination with other anti-cancer drugs, particularly in cases where the cancer cells exhibit the 17p deletion genetic abnormality, making them less responsive to standard treatments.
Buy high quality N-Nitroso Venetoclax Impurity 1 from Chemicea Pharmaceuticals. Chemicea Pharmaceuticals is one of the leading manufacturer and exporter of N-Nitroso Venetoclax Impurity 1

N-Nitroso Venetoclax Impurity 1

N-Nitroso Venetoclax Impurity 1
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CAT. No. CP-V17005
CAS. No. NA
Mol. F. C45H49ClN8O8S
Mol. Wt. 897.45
Stock Status Custom Synthesis
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Product Description


  • Category:Impurity Standards
  • Synonyms:NA
  • Chemical Name:2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(nitroso((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide

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