Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Nitrofurantoin . Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Nitrofurantoin is an antibiotic commonly used to treat urinary tract infections (UTIs). Its chemical structure involves a nitrofuran ring. Nitrofurantoin exerts its antimicrobial effects by interfering with the bacterial enzymes involved in energy metabolism, damaging bacterial DNA. Administered orally, this drug is particularly effective against urinary tract pathogens, providing a targeted and localized treatment. Nitrofurantoin is known for its low resistance development and is considered a first-line treatment for uncomplicated UTIs.
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