Tucatinib Impurity 7 with CAS No:937266-01-8 is an impurity standard of Tucatinib.
Tucatinib is a tyrosine kinase inhibitor with the chemical formula N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-([2-(methylsulfonyl)ethyl]amino)methyl-2-furyl]-4-quinazolinamine. It finds application as a targeted therapy for HER2-positive breast cancer, where overexpression of the HER2 protein is associated with aggressive tumor growth. By inhibiting the activity of HER2, tucatinib disrupts signaling pathways crucial for cancer cell proliferation. Typically administered orally, tucatinib is often used in combination with other anti-HER2 therapies and chemotherapy to improve treatment outcomes and slow down disease progression in advanced or metastatic HER2-positive breast cancer cases, contributing to enhanced overall survival rates.
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