Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Varenicline . Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Varenicline is a medication used to aid smoking cessation by helping individuals quit smoking. Structurally, it is a partial agonist of the nicotinic acetylcholine receptor. Varenicline acts on these receptors in the brain, both activating them to a lesser extent than nicotine and blocking nicotine from fully activating them. This dual action helps to reduce withdrawal symptoms and cravings associated with smoking. Administered orally, varenicline is typically prescribed as part of a comprehensive smoking cessation program. Its unique mechanism makes it effective in supporting individuals trying to quit smoking by mitigating the rewarding effects of nicotine.
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